Tuesday, November 8, 2011

Winner of Best Content in a Poster, Lynn Brockway

Lynn Brockway is a 2nd year Vet student at University of MO.
She was awarded the prize for the Best Content in a Poster at the International Equine Conference on Laminitis and Diseases of the Foot Oct 29-31 at West Palm Beach.
Her project has been partially funded by AHF through Dr. Phil Johnson's grant.

Click to view larger size

Saturday, October 15, 2011

Animal Health Foundation presents Trivia Night!

When: November 19, 2011
Time: 6pm (Doors open at 5.15pm) - Silent Auction ends after Round 7
Where: AKC Museum of the Dog
Queeny Park, 1721 South Mason Rd. St. Louis, MO 63131

Price: $200 for a table of 8 ($25 per person)
Price includes 1 bottle of wine and 1 bowl of snacks.
Tables are limited!  This is on a first come, first serve basis!  Reserve yours TODAY!

Please come join us for a fun and informal competition where teams battle to see who has the greatest knowledge of all things - well, trivial! All proceeds go towards the Animal Health Foundation and our continuing mission to find a cure for Laminitis.

Got a group already?  Please download this flyer and fill it out for us!

Don't have a group but want to come?  Post a call on our Facebook page and get a group together!

Silent Auction Contributors

The Dog Pound
Dead or Alive
Heads or Tails
50/50 tickets

We still need more Silent Auction contributions!  If you would like to donate an item to the Animal Health Foundation silent auction, please download and fill out this form.

Tell your friends!  Bring your family!  This is an event you will not want to miss!

Thursday, October 6, 2011

Field Treatment and Management of Endocrinopathic Laminitis in Horses and Ponies

Dr. Walsh promotes a method of early detection of the endocrinopathic form of Laminitis and explains how Veterinarians using a Laminitis Risk Evaluation form may help horse owners prevent the onset of laminitis .

This article appears in Veterinary Clinics of North AmericaAdvances in Laminitis – Part 2. It deals with one of the newest findings in laminitis research: the role of insulin in certain types of laminitis and how to prevent the disease from occurring.


Tuesday, August 30, 2011

Laminitis and founder: A look at the disease and leading researchers

Laminitis Research at the Australian Equine Laminitis Research Unit - Part 2

Laminitis Research at the Australian Equine Laminitis Research Unit - Part 2

From the desk of Dr. Don Walsh,

During the past five years a significant portion of research efforts at the Australian Equine Laminitis Research Unit (AERLU) have focused on development of an effective drug delivery system, targeting the laminae of the horse’s foot.  Pioneering work done under the supervision of Dr. Chris Pollit by Dr. Ali Nourian’s PhD thesis developed a method of intraosseous infusion (IO) of the distal phalanx (coffin bone) [IOIDP] of the horse’s foot in order to deliver drugs. My personal participation during the past two years at the laboratory has been to further test and develop the use of this drug delivery system. 

I must admit when I first learned of the idea of drilling a hole through the hoof wall into the bone to access the unique circulation of the distal phalanyx, I was skeptical.  I am from Missouri, the “Show Me State”.  I thought it would be too painful for the horse to endure, and I needed to be shown this would work.  Well, I was wrong and Drs. Nourian and Pollitt were right. Horses tolerate the presence of the needle in their foot with no discomfort.

The work I have been involved with the past two years has investigated the extent of the potential delivery of drugs within the lamellar circulation.   The delivery system will allow clinicians to deliver a drug into the intraosseous space inside the bone. This space has direct communication to the sublamellar vessels and the laminae tissue. A slow infusion through the needle allows drugs to be delivered to the laminae to prevent or treat laminitis. 

Further perfecting the Intraosseous methods and studying the complicated circulation of the intraosseous space is being done by Simon Collins, PhD who is completing a two year post doctrinal study of IOIDP. The general public probably has no idea of how much research it takes to develop something like this method. We have to be absolutely sure we are confident in the delivery system before it will be a useful tool to help horses with laminitis.

The Intraosseous Infusion Procedure is also of great benefit as a research tool when studying the effect of a drug therapy on the laminae.  Currently Dr. Claire Underwood, as part of her PhD project, is developing a monitoring system inside the hoof to measure different concentrations of drugs that may be administered  by the intraosseous method as well as other more conventional  drug delivery methods. Assisting her with this project is Dr. Carlos Medina Torres working on his PhD. Both are under the supervision of Dr. Pollitt and Dr. vanEps.

I want to convey to the reader the sheer number of researchers and the varied projects they are working on.  It is a many-faceted challenge and Dr. Pollitt and this team of scientists at AERLU are continually adding to the knowledge we have about laminitis and treating the disease. They are working with very limited resources and any donations to fund the laminitis research are greatly needed and appreciated.  Please consider supporting this work.  As always, one hundred percent  (100%) of all public donations to AHF go directly to fund laminitis research. 

Tuesday, August 9, 2011

Introducing Dr. Don Walsh

As an introduction, my name is Dr. Don Walsh and I am the founder and president of the Animal Health Foundation, which was started in 1984. I have retired from active practice as an equine veterinarian after 42 years as of July 1, 2011. This new freedom has allowed me to pursue my interest in laminitis and the work of the AHF on a full time basis. 

To that end I am now going to be much more engaged in writing for this website. Hopefully this endeavor will enable me to help educate veterinarians, farriers, and horse owners about the latest information regarding the disease. We have made a lot of progress in understanding laminitis and now we need to apply this information to help prevent laminitis from occurring in horses.

We are in the final process of producing a series of short videos which will be posted on the website. These videos will be a good source of information for people to understand the disease but more important prevent the disease from occurring in their horse.

Laminitis Research at the Australian Equine Laminitis Research Unit - Part One

 From the desk of Dr. Don Walsh,

For the past two years I have been spending half of my time engaged in several research projects at the Australian Equine Laminitis Research Unit at Queensland University in Brisbane, Australia as a Industry Fellow in the Veterinary Science department working with Professor Chris Pollitt. I am presently here at the unit finishing up some work, and have written about a conversation that I recently had with Dr. Pollitt about the current projects.

Laminitis Research at the Australian Equine Laminitis Research Unit - Part One

August 6,2011 - A meeting with Professor Chris Pollitt, the head of the AERLU unit at Pinjarra Hills, University of Queensland, Brisbane, Australia

Chris Pollitt and I have been friends since 1995, and AHF has been funding his research efforts since that time. When we met yesterday we reviewed what we have accomplished. We now understand a great deal more about how laminitis occurs and have definitely defined two pathways: 1) the enzyme activated inflammatory pathway associated with major changes in the bacterial flora of the hindgut of the horse, and 2) the endocrine pathway associated with elevations in insulin levels in the bloodstream of the horse often associated with grass consumption.

Much of the success of the Lab over the years has been due to the efforts of the PhD students under Dr. Pollitt’s supervision. Dr. Andrew van Eps’ work, demonstrating that icing horses’ feet would prevent laminitis, has provided us with the only known method to prevent laminitis and is routinely used today in treating and preventing laminitis around the world. Dr. Katie Asplin’s work revealed the role of insulin in causing laminitis. The PhD theses of Dr. Cathy French and Dr. Bruce Mungall explained the activation of protease enzymes in the feet that leads to the loss of the support of the distal phalanx, of the laminitis associated with many disease processes.

Yet in spite of the successful research of all these students we still do not completely understand the processes of laminitis. The two most recent PhD students, Dr. Michell Visser and Dr. Melody deLaat, have each added new information about both of the pathways. Dr Visser’s work has enabled us to understand the changes occurring in the first few hours when laminitis is developing in the enzyme activated form of laminitis. Dr deLaat has brought our understanding of the insulin form of laminitis to new heights.

Despite all this progress there are still important questions to be answered. However Dr. Pollitt feels we are very close, and likened the situation to peaking the summit of a mountain and viewing the destination on the far horizon for the first time. Sadly allowing Visser and deLaat to continue their research as post doctoral employees of the laboratory is likely not going to happen because of a lack of funding.

Dr. Pollitt feels that if we were able to finance their salaries and research expenses as post doctoral scholars we would likely be able to conquer both forms of the disease. The cost to accomplish this would be approximately $600,000 over the next three years. While this is a sizable sum, it is very little in comparison to most medical research projects costing millions. Our ability to fund equine research falls back on the shoulders of horse owners and equine organizations, as government agencies have very little interest in horse research projects.

I am asking all of you to consider making regular donations to the AHF to help fund these important projects. If everyone who has a horse would make a small donation it would make a huge difference. Please consider my plea for your help.

Tuesday, June 21, 2011

Major Breakthrough in Understanding Insulin Form of Laminitis

Researchers funded by the Animal Health Foundation announced June 15, 2011, that they have made a major breakthrough in understanding how the insulin form of laminitis occurs.

Drs. Melody de Laat and Chris Pollitt of the Australian Equine Laminitis Research Unit at the University of Queensland have discovered that receptors designed to receive insulin-like growth factor 1 (IGF-1) may be binding to insulin instead in horses with high levels of insulin.

This groundbreaking discovery may enable scientists to develop strategies to try to block IGF-1 receptors from receiving insulin and prevent the disease from occurring.

Tuesday, May 3, 2011

Hoof care professionals: First line of defense in prevention of laminitis

Dr. Don Walsh, president of the Animal Health Foundation, gave Natural Hoof Care professionals an important point to be aware of regarding laminitis and its prevention.
Dr. Donald Walsh, AHF President, during his presentation at the Liberated Horsemanship Clinic in April.

The presentation entitled “You, the hoof care giver, are the first line of defense in preventing laminitis” was heard by attendees of the Liberated Horsemanship Clinic held April 16, 2011 in Warrenton, MO, sponsored by Dr. Bruce Nock, PhD.

Tuesday, February 22, 2011

Dr. Walsh Speaks at International Hoof-Care Summit

Dr. Don Walsh spoke to attendees of the Eighth Annual International Hoof-Care Summit held Feb. 1-4, 2011 in Cincinnati, Ohio.  The meeting theme, “Coming together for better hoof care”, brought the latest, most innovative and forward-thinking information and ideas regarding the equine foot from hoof-care specialists from around the world.

Dr. Don Walsh speaking at the International Hoof-Care Summit
 in Cincinnati, Ohio Feb. 1-4 2011
Dr. Walsh’s presentation, “Laminitis: Your Critical Role in Early Detection of the Disease Process”, described the early changes in the growth pattern in the hoof that may first be seen by the hoof care professional when trimming or shoeing a horse. These changes are seen when abnormally high levels of insulin are present in the blood, which could lead to laminitis, but before any sign of lameness occurs.

When these early changes appear, Dr. Walsh suggests that owners be notified and encouraged to establish communication with their veterinarian to test the fasting blood level of insulin.  Proper care including a low glycemic diet, increasing exercise, and medications if necessary can bring the insulin level back down into the normal range.  With proper trimming and hoof care laminitis can be prevented and a normal hoof re-grown.

As Dr. Walsh says, “Prevention is always preferable to treatment”, when it comes to laminitis.  This form of the disease causes slow changes in the foot, which can be reversed if detected early by farriers, hoof-care givers and veterinarians.

Tuesday, January 11, 2011

Dr. Walsh’s Memoir of Treating Laminitis

Dr. Don Walsh
Using his experience resulting from dealing with laminitis in private practice for over 40 years, Dr. Walsh offers a comprehensive look at the historical background of the disease and an overview of methods used in the treatment of equine laminitis.

The following is a chapter which appears in Veterinary Clinics of North America, Advances in Laminitis – Part 1, a compilation of the most recent findings regarding equine laminitis. Contributors to the publication are leaders representing all aspects of research into the disease.